France BioImaging is the French Node of Euro-BioImaging ERIC and participates to the Euro-BioImaging ERIC activities. As such, France BioImaging core facilities are opening their premises to EuBI users for transnational and national access.
France BioImaging offers to EuBI users:
- Access to 17 biological imaging facilities and laboratories specializing in R&D for imaging in 6 regional nodes
- A waiver for the costs of instrument use (up to 750€ per week)
- A wide range of technical and methodological expertise: Single Particle Tracking & Super Resolution / Multimodal & Quantitative fluorescence Microscopies / Multiscale & Correlative Microscopy / New Contrast & In-Depth Imaging / High Throughput & High Content Screening / Probe development, Optomanipulation & Optogenetics / BioImage Informatics, Image Processing & Data Management
- Strong support in computational analysis, provide quantitative measures and integrative understanding of a wide range of cell and tissue activities in biological models, from the simplest, to small animals in normal and pathological situations
This call for scientific projects is open to any users outside France BioImaging Research Infrastructure perimeter, who would like to use imaging technologies in one of FBI nodes: Paris Centre, Paris Ile-de-France-Sud, Marseille, Montpellier, Bordeaux, Bretagne-Loire.
The eligibility criteria are:
- the project must be based on one of the EuBI technology portfolio (see list below)
- a suitable scientific environment, possibly collaborative (example: neurosciences, cancer research… )
Access requests can be submitted at any time through EuBI Web Access Portal : https://www.eurobioimaging.eu/service
More info on EuBI access application process: https://www.eurobioimaging.eu/about-us/how-to-access
Note: We encourage users to discuss potential applications with the contact person at the prospective France BioImaging core facility before submitting an application, to make the application as strong and successful as possible. Users can also contact France BioImaging coordination team for further information.
Offered technologies @France – French BioImaging Node
- Deconvolution widefield microscopy
- Laser scanning confocal microscopy (LSCM)
- Multiphoton systems
- Spinning disc confocal systems
- Total internal reflection fluorescence microscopy (TIRF)
- Fluorescence correlation spectroscopy (FCS)
- Fluorescence cross-correlation spectroscopy (FCCS)
- Fluorescence-lifetime imaging microscopy (FLIM)
- Fluorescence resonance energy transfer (FRET)
- Fluorescence recovery after photobleaching (FRAP)
- Raman Spectroscopy
- High Throughput Microscopy
- Electron microscopy
- Correlative light electron microscopy (CLEM)
- Digital scanned laser light-sheet fluorescence microscopy (DSLM)
- Objective-coupled planar illumination (OCPI)
- Optical projection tomography (OPT)
- Selective plane illumination microscopy (SPIM)
- Ground state depletion microscopy (GSD)
- Photo activated localization microscopy (PALM)
- Reversible saturable optical fluorescence transitions (RESOLFT)
- Stimulated emission depletion microscopy (STED)
- Stochastic optical reconstruction microscopy (STORM)
- Atomic Force microscopy (AFM) *
Review of the application
Every application will go through two stages of evaluation. The criteria for the evaluation can be found in the Review of applications tab. The first evaluation stage is a scientific review, conducted by two external reviewers, who are leading experts in the field. After the first review, if any additional information is required, you will be invited to submit it via the EuBI Web Access Portal. If the application passes the first review, it will be sent to France BioImaging for a technical feasibility review. Again, you will be invited to submit additional information, if needed. You will be constantly informed of the progress of the application procedure by email. The whole procedure, until final notice of acceptance/rejection, is expected to take 3-4 weeks.
After successful application evaluation
After your application has been accepted, you will be contacted by France BioImaging contact person for further practical arrangements, including project preparation and time and duration of your visit.
During the visit
At FBI core facility, an effort will be made to serve you in the best possible way. You will receive hands-on training for the technology(ies) you will use, access to equipment and materials, and expert support with data collection and analysis. You will also be given guidance for the transport of materials, made aware of health and safety regulations and provided help with accommodation arrangements.
After the visit
After you have completed the visit, you will be required to fill in a brief online feedback form via the Web Access Portal. Later, when the project your visit was part of is completed, you need to remember to fill in a brief concluding report that includes information of a possible scientific publication.
Euro-BioImaging ERIC and France BioImaging access needs to be acknowledged in any publication with a sentence such as the following: “The authors acknowledge Euro-BioImaging ERIC (www.eurobioimaging.eu) for providing access to imaging technologies and services via France BioImaging core facility XXX (City, France)”.
Note: Filling in these post-access feedback forms is mandatory, as they are essential for EuBI and France BioImaging to continuously optimize their services and to get statistics and information necessary for justifying continued operations.