Cellular imaging for neurodegenerative diseases studies : nervous system, neurons in culture, cell biology, cytoskeleton

Rats, mice, non-human primates, mussels, shrimps, copepods

Phytotronic cabinets and expression of fluorescent fusion proteins/tags (transformation by electroporation)

All equipment necessary for cell culture (PSM, incubators, centrifuges, etc.)

Numerous tests to monitor the performance of photonic microscopy systems, including light source power, observation field homogeneity, detector stability, etc. Training at PRIMACEN or at the applicants’ site.

Advice and production of image competitions and photo exhibitions
(Keywords : rules for an image competition, totem for outdoor display, dibond printing)

Core Facility Management Software (home-made development)
(Keywords : user management, instrument management, booking website, user autonomy management, dysfunction management, usage reports at different levels, invoicing)

Training portfolio (BioCampus workshops recognized by CNRS, INSERM, INRAe, University’s continuing training courses):
(Keywords : basis of microscopy, Advanced training about high resolution microscopy, basis of flow cytometry, FlowJo, basis of image processing and analysis, Fiji macros, 3D-analysis, machine/deep learning, QuPath))

X-ray Microtomography of large samples (1mm up to 30cm in diameter)
(Key words : 3D volumetric acquisition; large samples; non-invasive inspection; tomodensitometry)

Hight-throughput and high content screening : from sample preparation, automation in sample preparation, data acquisition (plate reader or microscopy), image analysis and statistics analysis (list of hits)
(Key-words: chemical libraries, siRNA libraries, sgRNA CRISPR-Cas9 arrayed libraries covering entire genomes (human and mouse), automatic platform for sample preparation, HCS microscopes with low and high resolution, flow cytometer with images)