Gene expression, DNA damage, DNA structure and DNA-binding proteins structures, super-resolution (SMLM, RIM, SIM, Airyscan), single particle tracking, photo-manipulation, Correlative Light Electron Microscopy (CLEM)
Main Category: Super-resolution microscopy
Low signal fast live imaging at nano-scale level (Airy / Fast Airyscan , Live-3D-STED, Live-3D-SLMN)
Cell-biology expertise: providing cells(epithelial, glial, neuronal) and organoïds, labelling (transfections or probe-Test), and imaging for physicist, chemist that would like to test a prototype. Including : Guidance on super-resolution modalities (collaboration) : from system choice (SIM-STED-STORM) to images processing and data analysis (tools development).
ExM cell & tissue : ProExM, TREx, ExSTED ExPath
:STED-FLIM BSL-2 : Live / 3D / multi-labeling
Expertise in preparation of sample in expansion microscopy coupled with microscopy high resolution and lightsheet
Airyscan, SIM, STORM modes
Super-resolution acquisition coupled to high-end atomic force microscopy
Full pipeline support on single molecule microscopy equipment (from sample to data analysis)
Stellaris 8, WLL, FALCON, 592 and 775 nm for depletion, Leica Microsystems
Super-resolution-based imaging for cell, tissue and embryo : from sample preparation, to imaging & data processing
(Key-words: Airyscan, STED, STORM, PALM, expansion microscopy alone or combined with other super-resolution technics, data analysis)