On-demand workflow design for image processing and analysis

Cellular imaging for neurodegenerative diseases studies : nervous system, neurons in culture, cell biology, cytoskeleton

Quantitative measurement of intracellular forces on living cells, but also within tissues (Drosophila, pupae, mouse intestines). Mechanotransduction, micro-nanorheology. High-resolution fluorescence imaging using remote focusing coupled with force measurements.
Compression force measurements

Bruker 2P+, Discovery laser (680 to 1340 nm), mouse anesthesy and stabulation. Cleared mouse organs (gut, lymph nodes..) and 2P microscopy

To decipher Inflammatory and cardiovascular diseases, multiplex imaging and cytometry pipelines include the entire process from sample preparation, image acquisition to image analysis and quantification. Our workflows are adpated to mouse or human lymphoid organs and blood . They employ techniques such as confocal spectral imaging and cytometry-based analysis (spectral, sorting, and analysis).

Light-sheet imaging of fixed and live samples. We can afford (cells, IPS, organoïds, hydra, fish, human tissues) because the microscope is installed in Biology Safety Level 2

Ultrafast in vivo functional optical imaging using AOD two-photon microscopy (brain slices and small animals)

Full pipeline support for single molecule RNA FISH

Rats, mice, non-human primates, mussels, shrimps, copepods

All equipment necessary for cell culture (PSM, incubators, centrifuges, etc.)

Workflow including sample preparation, 2P microscopy, confocal microscopy, light sheet microscopy, ophthalmic imaging/OCT/ERG and image analysis.