Studying cellular processes, probing the functionality of specific proteins and organelles using photomanipulation techniques within living samples

Several modules or lasers are available for specific photomanipulation experiments at the sub-cellular level: high energy 355 nm pulsed lasers allow uncageaging, DNA damage induction, or precise photoablation (available on a TCS SP8 confocal microscope or on fast spinning disk with Yokogawa CSU X1 scanning head), laser microdissection system, Multiphoton confocal system also available for localized damage or precise ablation, FRAP module available on 2 confocal systems and on 2 spinning disk (equipped with liveSR module), allowing the analysis of intracellular dynamics, controlled photoactivation or photoconversion applications.
Following acquisition, solution or assistance for quantitative data analysis, curve fitting and kinetics measurements can be provided.