Microglia’s attack!

Microglia's attack! © Françoise Geffroy, CEA-DRF-NeuroSpin-UNIRS, Midas Team

(Widefield fluorescence microscopy using structured illumination)

Mouse APP/PS1 is a model of Alzheimer disease and old one have lot of amyloïds aggregates. In this picture, microglial cells stained with an antibody against IBA1 (red) attack amyloïds aggregates, colored with thioflavine S (green).