France-BioImaging operational level relies on various Working Groups (WGs) described below. They gather trans-node and external experts in the corresponding domains.

Their aims are to:
• Define new technological and methodological developments,
• Solve eventual barriers in sharing methods and techniques,
• Organize training, transfer and communication for user access to emerging technologies and methods.

All Working Groups stand at least once a year and report their results and proposals to the Executive Board and to the National Advisory Committee during France-BioImaging annual meeting.

Some events are organized by each Working Group, as workshops or webinars, to allow the meeting of all the Working group members.