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France BioImaging

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Camille Boutin & Nicolas Brouilly SEM picture of Xenopus epidermal multiciliated cells

We’ve got many news and upcoming events to share with you! Here is a quick rundown.
 

Welcome to our new nodes!

We are delighted to announce that two new nodes are joining France-BioImaging: the Alsace Node and the Toulouse Node!

Located in Strasbourg, Illkirch and Mulhouse, the Alsace node is offering high level technical and innovative methodological expertise in multi-scale imaging at the interface between biology, chemistry, optics and physics, from the atom to the small animal/plant.

The Alsace Node has a strong expertise in probes with the development of highly innovative fluorescent probes and luminescent nanoparticles  and provides cutting-edge technologies and methodologies, with, among others Tomographic Diffractive Microscopy, Single particle tracking and time-resolved luminescence microscopy or SharpViSu & ClusterViSu, integrated software for image analysis of labeled complexes.

The Toulouse node is composed of a large nationally recognized multi-site core facility. Four scientific axes are conducted: mechano-biology, molecules and single cells, whole organisms, image processing and quantitative data analysis.

The mission of the node is also to develop original devices to explore biophysical properties in living samples, to work at the interface between machine and sample and to develop artificial intelligence applied to bioimaging. The node provides cutting-edge technologies and methodologies, with among others, Random illumination microscopy, Protrusion force microscopy, ANchOR technology, a florescent labeling system of genomic site with small DNA insert or 3D bioprinted scaffolds for organoids.

Welcome to the France-BioImaging family!

 

First AI4Life Open Call for Bioimage Analysis Support!

The European project AI4Life aims at narrowing the gap between life scientists performing biological imaging and developers of AI-based methods to analyze microscopy image data.

This is the first of a series of annual open calls, meant to provide life scientists who have unmet image analysis needs with adequate deep learning enhanced workflows for their desired analyses.

The call welcomes proposals for projects from anyone who operates on life-science image data and has the interest to evaluate, together with our AI4Life team, if modern deep learning-based methods can improve your analysis workflows.

Learn more about the call: https://ai4life.eurobioimaging.eu/first-open-call/

 

Reminder: FBI launches 2 calls for funding - Africa-France Joint Initiative for Biological Imaging

France-BioImaging, partnered with the African BioImaging Consortium and Imaging Africa, has announced our first open calls for projects to support collaborative initiatives between African and French scientists from all fields where biological imaging became essential! 

The two calls have been designed to strengthen collaboration between African and French researchers and engineers, with different approaches:

  • Call 1) External Access: African user projects that will demonstrate the need for at least one technology and/or expertise available in a FBI core facility or R&D team, that is not readily available on the African continent (up to 5k€)
  • Call 2) Twinning Exchange Program: Bilateral exchange of personnel between an imaging facility or a laboratory in Africa and one of its counterparts within the FBI perimeter. This exchange is focused on service activities and practices, training approaches and comparison of needs (up to 4k€)

Submit your project proposal through the France-BioImaging web portal before April 30st, 2023. Successful applicants will be notified by late September 2023 and successful projects should be started before March 2024. 

Applicants are invited to visit our website to discover the range of technologies provided by France-BioImaging Nodes: https://france-bioimaging.org/services/

Applications have to be submitted here: https://france-bioimaging.org/application/africa-france-joint-initiative-for-biological-imaging/

 

A novel label-free microscopy technique to image red blood cells and oxygenation

Researchers from the Laboratory for Optics and Biosciences, a member of the Ile-de-France Sud node of France-BioImaging, and from the Developmental Biology and Stem Cells Department, developed a new form of multiphoton microscopy providing label-free imaging of red blood cells and oxygenation. This technique is called color third-order sum-frequency generation microscopy. As described in an article recently published in Light: Science & Applications, blood circulation could be imaged faster with this novel microscopy approach.

Learn more about this article: https://france-bioimaging.org/announcement/publications/image-red-blood-cells-and-oxygenation/

 

FBI.data Sprint: a week to work on FAIR image data management

From February 6th to February 10th, France-BioImaging organised a group meeting on the project “FBI.data” in Bordeaux. For a week, participants focused on the architecture and the implementation of image data management tools. A user-friendly response to the challenges of never-ending data production. 

New Imaging technologies are very greedy in terms of image processing and data management. Beside the image itself, biological imaging generates a huge amount of metadata. The FBI.data project, one of the key missions of France-BioImaging, addresses the questions related to the computational analysis and handling of image data.

Learn more: https://france-bioimaging.org/announcement/news-from-nodes/fbi-data-sprint-a-week-to-work-on-fair-image-data-management/

 

A powerful high speed, low phototoxicity microscopy method to achieve super-resolved images

Are you interested in looking at tissues or other thick samples in high resolution? Marc Tramier, from the Bretagne-Loire Node of France-BioImaging, offers RIM as a Euro-BioImaging Proof-of-Concept study, and is now accepting applications for projects.

The idea of Random Illumination Microscopy is to use the speckle of the illumination laser in wide field to create a structured illumination pattern at the diffraction limit. By varying the pattern from image to image using a diffracting element, scientists are able to acquire a stack of images on a camera which corresponds to a cumulative homogeneous illumination. By resolving the inverse problem, a super-resolved image is, then, reconstructed, at the focal plane with unprecedented optical sectioning. In comparison to conventional SIM, RIM is able to work in depth inside diffusive samples as the speckle is insensitive to diffusion.

RIM is one of the powerful methods to achieve super-resolved images in depth at high speed with very low phototoxicity. This makes a very nice compromise of z-sectioning and super-resolution with wide field illumination particularly adapted to thick live samples. 

Learn more: https://france-bioimaging.org/announcement/news-from-nodes/random-illumination-microscopy-article/

Watch this short video about the RIM: https://www.youtube.com/watch?v=6iy-XbZ4FrE

 

News & Events

23 Jan, 2023
Africa-France Joint Initiative for Biological Imaging
13 Mar, 2023
FBI CLEM day
20 Mar, 2023
Pushing the frontiers of dynamic imaging
21 Mar, 2023
Euro-BioImaging User Forum “Cardiovascular Research”
23 Mar, 2023
Videoconference : Click chemistry, bioorthogonal chemistry, and imaging. From concepts to the Nobel Prize
13 Apr, 2023
15th IEEE EMBS-SPS International Summer School on Biomedical Imaging
 

Trainings

Training
28/03/2023 9:00 am
Cytometry Workshop
 

Job Offers

Scientist
02 March, 2023
Ingénieur.e d’étude – Plateforme De Microscopie Photonique de l’IGBMC (Illkirch)
Scientist
10 February, 2023
Poste à la mobilité : Ingénieur de recherche en calcul scientifique et microscopie optique (Paris Centre, Rennes)
 
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