France BioImaging is the French Node of the European infrastructure Euro-BioImaging that provides access to imaging technologies in 14 different countries across Europe.

As such, France BioImaging invites all its external users* to register through Euro-BioImaging web portal to access any equipment available on France BioImaging facilities and labs.

By registering through the EuBI web portal, France BioImaging users will:

  • have access to 24 biological imaging facilities and laboratories specializing in R&D for imaging in 6 regional nodes
  • receive a waiver for the costs of instrument access (up to 750€ per week) on FBI facilities (1).
  • have access to a wide range of technical and methodological expertise: Single Particle Tracking & Super Resolution / Multimodal & Quantitative fluorescence Microscopies / Multiscale & Correlative Microscopy / New Contrast & In-Depth Imaging / High Throughput & High Content Screening / Probe development, Optomanipulation & Optogenetics / BioImage Informatics, Image Processing & Data Management
  • receive a strong support in computational analysis, provide quantitative measures and integrative understanding of a wide range of cell and tissue activities in biological models, from the simplest, to small animals in normal and pathological situations

Procedure

  1. Go to the Euro BioImaging website: https://www.eurobioimaging.eu/service, click on “biological Imaging”, select the technology that will be used and the host node (French BioImaging Node). Then you will have to click on “select” (available service section). 
  2. “Name_of_the_Technology @ France – French BioImaging Node” will appear and you will have to click on “make a proposal”. See the list of technologies available below.
  3. You will then be redirected to the Elixir page to create an account and register your project. You should find your home institution in the institution list, otherwise there are alternatives (Google, ORCID, etc.) 
  4. Submit your proposal: Once you are logged in through Elixir, fill in and submit the simple proposal form (see https://www.eurobioimaging.eu/about-us/how-to-access for an overview of the form). NB: It is important to highlight the imaging aspects of the project and their importance, as well as to mention that contact has already been established with the France BioImaging facility/lab and the name of your contact on site. Also, if the project has already undergone an external scientific evaluation (i.e. for a grant) it is important to mention it, since it will greatly speed up the acceptance by Euro BioImaging.

*This registration process is open to:

  • any users from outside the institutional perimeter of France BioImaging nodes (i.e. from outside the following institutions: Aix-Marseille Université, Université de Montpellier, Université de Bordeaux, Université de Nantes, Université de Rennes 1, Université Paris-Saclay, Université de Paris, Université PSL -Paris Sciences & Lettres-, Généthon, Ecole Polytechnique, Institut Pasteur) who would like to use imaging technologies in one of FBI nodes: Paris Centre, Paris Ile-de-France-Sud, Marseille, Montpellier, Bordeaux, Bretagne-Loire. They can be French or international users – EU and non-EU
  • or users from a France BioImaging regional Node who want to access an equipment available in another FBI regional node.

(1) Restrictions: This waiver does not apply for companies.

Questions? Contact us: France BioImaging coordination team


Offered technologies @France – French BioImaging Node
  • Deconvolution widefield microscopy
  • Laser scanning confocal microscopy (LSCM)
  • Multiphoton systems
  • Spinning disc confocal systems
  • Total internal reflection fluorescence microscopy (TIRF)
  • Fluorescence correlation spectroscopy (FCS)
  • Fluorescence cross-correlation spectroscopy (FCCS)
  • Fluorescence-lifetime imaging microscopy (FLIM)
  • Fluorescence resonance energy transfer (FRET)
  • Fluorescence recovery after photobleaching (FRAP)
  • Raman Spectroscopy
  • High Throughput Microscopy
  • Electron microscopy
  • Correlative light electron microscopy (CLEM)
  • Digital scanned laser light-sheet fluorescence microscopy (DSLM)
  • Objective-coupled planar illumination (OCPI)
  • Optical projection tomography (OPT)
  • Selective plane illumination microscopy (SPIM)
  • Ground state depletion microscopy (GSD)
  • Photo activated localization microscopy (PALM)
  • Reversible saturable optical fluorescence transitions (RESOLFT)
  • Stimulated emission depletion microscopy (STED)
  • Stochastic optical reconstruction microscopy (STORM)
  • Atomic Force microscopy (AFM) *

Questions about the available technologies and feasibility should be addressed directly to the heads of the France BioImaging facilities.


General conditions

Waiver of costs

The following costs are eligible for financial support:

  • Contribution to the verifiable incurred costs for measurement – data acquisition
  • Imaging related sample preparation (special chemicals, labels, etc.)
  • Data processing and analysis

France BioImaging financial support will be transferred directly to the France BioImaging core facility/lab in which the project will be performed. The support does not include travel costs, accommodation and daily allowances. This has to be covered by the user.

Acknowledgements

Publications resulting from work undertaken at France Bioimaging facilities/labs have to contain the following acknowledgement:

“The National Infrastructure France-BioImaging supported by the French National Research Agency (ANR-10-INBS-04)”

Depending on the context, we suggest two model sentences:

  • For the publications of scientists using one of the France-BioImaging Imaging Facilities:  “We acknowledge the X (name of imaging facility), member of the national infrastructure France-BioImaging supported by the French National Research Agency (ANR-10-INBS-04)”
  • For the publications by FBI members (technological development or scientific projects and collaborations) the sentence must appear in tributes as follows: “We acknowledge France-BioImaging infrastructure supported by the French National Research Agency (ANR-10-INBS-04)