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Job offer

@ Centre de Biologie Structurale, Montpellier

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Engineering positions on spatial genomics

Organization: Centre de Biologie Structurale, Montpellier

Location: Centre de Biologie Structurale, Rue de Navacelles, Montpellier, France
Available from: January 1, 2026
Send CV, publications, summary and references to:
CNRS Jobs at https://emploi.cnrs.fr/Offres/CDD/UMR5048-FLOLEP-117/Default.aspx

Position Information:

Marcelo Nollman’s team in CBS (Center for Structural Biochemistry, Montpellier), is looking for two engineers to work on spatial genomics. The team is interested in understanding the mechanisms of DNA organization and remodeling by building state-of-the-art microscopes, and image analysis tools.

Project 1

The project 1 is centered on the use spatial genomics to investigate the mechanisms driving chromatin organization during meiosis in mice.

Candidate 1 will have expertise in microscopy and/or molecular biology, and will be in charge of amplifying oligopaint libraries, performing DNA-FISH, preparing chromosome spreads/squash from spermatocytes, and acquiring and analyzing spatial genomics datasets.

Project 2

The project 2 consists in the development of imaging-based spatial multi-omics to visualize epigenetic marks and 3D chromatin organization in Drosophila, mouse and human samples.

Candidate 2 will have experience in molecular biology and sequencing-based technologies, and will be in charge of designing and validating spatial multi-omics strategies to image epigenetic marks in cancer models.

Find more details on the projects on the PDF attached.

General informations

Starting date: As early as 1 January 2026

Deadline for application: November 10, 2025

Send your CV with letter of motivation at: https://emploi.cnrs.fr/Offres/CDD/UMR5048-FLOLEP-117/Default.aspx

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