Postdoctoral researcher position in quantitative fluorescence microscopy applied to mitochondria
Organization: Institut de Génétique & Développement de Rennes
Position Information:
Missions
We welcome a highly motivated post-doctoral researcher to join our group at the Institute of Genetics and Development of Rennes (IGDR), France (https://igdr.univ-rennes.fr/en). The research in our team focuses on state-of-the-art quantitative fluorescence microscopy methods and tools to study the spatiotemporal regulation of protein-protein interactions and biochemical activities at the mitochondrial level. The postdoc will be under the supervision of Dr. Giulia Bertolin, CRCN CNRS, and will work on the use and on the functional validation of FRET-based biosensors for mitochondrial functionality.
Activities
– Implement innovative protocols and data analysis pipelines for FRET and super-resolution microscopy in mammalian cultured cells
– Modify and/or create molecular biology tools (i.e. molecular cloning, mutagenesis etc.) and required for microscopy experiments
– Data analysis, presentation and publication
– Present data at conferences and contribute to grant applications within the team
– Mentoring undergraduate and master students within the team
Skills
– Hold a PhD in molecular biology, cell biology, biochemistry or closely-related disciplines
– Have a strong expertise in high/super-resolution microscopy (i.e. Airyscan, dSTORM etc.). Some knowledge of FRET would be a plus.
– Be proficient in experimental design, data analysis, and communication within the team and at the national/international level
– Be able to work both independently and collaboratively within the team and at the national/international level
– Be fluent in English and be ready to work with an international group
Context
We are thrilled to welcome a highly motivated Postdoctoral Researcher to join our dynamic group at the Institute of Genetics and Development of Rennes (IGDR), France (https://igdr.univ-rennes.fr/en). Research in our team focuses on state-of-the-art methods and tools in quantitative fluorescence microscopy to investigate the spatiotemporal regulation of protein-protein interactions and biochemical activities at mitochondria (see Bertolin et al ACS Sensors 2019 DOI: 10.1021/acssensors.9b00486; Durel et al, Biol Cell 2021 DOI: 10.1111/boc.202100021, Gökerküçük et al, Autophagy 2023 DOI: 10.1080/15548627.2023.2179845).The IGDR is a dynamic and expanding institute, with 15 teams including 200 international researchers and staff. Research at the IGDR covers a wide range of subjects in cell biology, taking advantage of classical model systems while strongly promoting interdisciplinary approaches, particularly at the interface between physics and biology. The institute also benefits from state-of-the-art core facilities, particularly in microscopy (Microscopy Rennes Imaging Center, MRic, https://microscopie.univ-rennes1.fr/). Rennes is the capital of Brittany (northwestern France), with easy and direct access to Paris (1.5 hours by train). Its rich tradition of cultural, musical and artistic events, as well as its close proximity to the coast, makes it a very welcoming and pleasant place to live.
More information on https://emploi.cnrs.fr/Offres/CDD/UMR6290-GIUBER-003/Default.aspx?lang=EN