The SIMS Group (Signal, Image and Sound) develops its research in the field of statistical signal and image processing. Tackling ill-posed inverse problems such as deconvolution and diffraction tomography is one of our main fields of expertise. We also focus on computational imaging issues, relying on mathematical tools from both optimization and Bayesian simulation fields. The optimal co-design of computational imaging systems is among our growing topics of interest, with the viewpoint of information theory. In the area of fluorescence microscopy, we investigate the superresolution capacity of random illumination microscopy, in collaboration with Institut Fresnel (Marseille) and the Centre for Integrative Biology (Toulouse).