The Bordeaux node is centered on the Bordeaux Imaging Center core facility that provides service training and R&D in photonic and electronic imaging, surrounded by 9 R&D teams. The strength of the Bordeaux node lie in the strong integration of physics at the LP2N (IOGS), imaging, chemistry and neurobiology at IINS and plant science at LBM. Bordeaux is a flagship center for super resolution imaging, both using photonics and electronic microscopies, applied to Neuroscience and Plant biology.

2021 in numbers

  • 180 projects hosted
  • 49 publications
  • 11 training programs
Actin fireworks© Patrice Mascalchi, Bordeaux Imaging Center and Frédéric Saltel, INSERM U-1053, University of Bordeaux

Technological Innovations

  • Lattice-STED Microscopy (Optics Express, 2014)
  • Single Obj. SPiM (Nat. Methods, 2015)
  • SR-tesseler (Nat. Methods, 2015)
  • SPT in brain slices (Nat. Comm, 2016)
  • Multi-Protein printing (Advanced Mat., 2016)
Sebastien Marais, Daniel Choquet - BIC

Most innovative systems available for booking

  • STED microscopy
  • Ultramicroscopy
  • FLIM spinning-disk microscopy
  • In-vivo multiphoton microscopy
  • MEB-triview
Magali Mondin, Daniel Choquet (CNRS Photothèque)

Tech transfer

  • Software for super-resolution microscopy licensed to Molecular Device
  • Single Objective Spim light sheet technology patented (commercialisation ongoing)
Facility

Bordeaux Imaging Center

↗ Website ↗ Service + Info

Facility: Bordeaux Imaging Center

Head: Daniel CHOQUET

bic@u-bordeaux.fr
Bordeaux Imaging Center, BIC, Bordeaux, France

The BIC (Bordeaux Imaging Center) offers resources in photonic and electronic imaging, mainly in life, health and plant sciences. It is a core facility identified at the national level as IBISA that gathers 12 highly skilled engineers. It has the ISO9001 label. The different components of the BIC are: PHOTONIC imaging, ELECTRONIC imaging, PLANT imaging. The Bordeaux Imaging Center offers access to the most advanced bio-imaging techniques for fixed and live cell imaging such as video-microscopy, confocal microscopy, multiphoton microscopy, transmission electron microscopy and scanning electron microscopy. The BIC provides a unique set of high-end equipment for super- resolution microscopy such as STED confocal microscopy, FRAP video-microscopy, lifetime imaging FLIM for the measurement of molecular interactions. We also provide access to equipment for sample preparation such as ultra-microtoms, high pressure freeze (HPF) and we can host live samples.

Microscopy systems available @BIC

Services on this Facility

Service

Microscopy Technologies

R&D team

Synapse Organization team – IINS

↗ Website + Info

R&D team: Synapse Organization team – IINS

Head: Daniel CHQOUET

daniel.choquet@u-bordeaux.fr
Centre Broca Nouvelle Aquitaine, Rue Léo Saignat, Bordeaux, France
R&D team

Cytoskeleton team – IINS

↗ Website + Info

R&D team: Cytoskeleton team – IINS

Head: Gregory GIANNONE

gregory.giannone@u-bordeaux.fr
Centre Broca Nouvelle Aquitaine, Rue Léo Saignat, Bordeaux, France
R&D team

Neuronal Development team – IINS

↗ Website + Info

R&D team: Neuronal Development team – IINS

Head: Laurent GROC

laurent.groc@u-bordeaux.fr
Centre Broca Nouvelle Aquitaine, Rue Léo Saignat, Bordeaux, France
R&D team

Morpho Plasticity team – IINS

↗ Website + Info

R&D team: Morpho Plasticity team – IINS

Head: Valentin NAGERL

valentin.nagerl@u-bordeaux.fr
Centre Broca Nouvelle Aquitaine, Rue Léo Saignat, Bordeaux, France
R&D team

Membrane Traffic team – IINS

↗ Website + Info

R&D team: Membrane Traffic team – IINS

Head: David PERRAIS

david.perrais@u-bordeaux.fr
Centre Broca Nouvelle Aquitaine, Rue Léo Saignat, Bordeaux, France
R&D team

Quantitative Imaging team – IINS

↗ Website + Info

R&D team: Quantitative Imaging team – IINS

Head: Jean-Baptiste SIBARITA

jean-baptiste.sibarita@u-bordeaux.fr
Centre Broca Nouvelle Aquitaine, Rue Léo Saignat, Bordeaux, France
R&D team

Organ-izing the cells team – IINS

↗ Website + Info

R&D team: Organ-izing the cells team – IINS

Head: Vincent STUDER

vincent.studer@u-bordeaux.fr
Centre Broca Nouvelle Aquitaine, Rue Léo Saignat, Bordeaux, France
R&D team

NanoBio Microscopy team – LP2N

↗ Website + Info

R&D team: NanoBio Microscopy team – LP2N

Head: Laurent COGNET

laurent.cognet@u-bordeaux.fr
Institut d'Optique Graduate School Nouvelle Aquitaine, Rue François Mitterrand, Talence, France
R&D team

Nanophotonique team – LP2N

↗ Website + Info

R&D team: Nanophotonique team – LP2N

Head: Brahim LOUNIS

brahim.lounis@u-bordeaux.fr
Institut d'Optique Graduate School Nouvelle Aquitaine, Rue François Mitterrand, Talence, France
R&D team

BioImaging OptoFluidics team – LP2N

↗ Website + Info

R&D team: BioImaging OptoFluidics team – LP2N

Head: Amaury BADON

contact@biof-lab.org
Institut d'Optique Graduate School Nouvelle Aquitaine, Rue François Mitterrand, Talence, France
R&D team

Plant Plasmodesmes team – LBM

↗ Website + Info

R&D team: Plant Plasmodesmes team – LBM

Head: Emmanuelle BAYER

emmanuelle.bayer@u-bordeaux.fr
INRAE Bordeaux-Aquitaine, Avenue Edouard Bourlaux, Villenave-d'Ornon, France
R&D team

Lipids in Plant Autophagy – LBM

↗ Website + Info

R&D team: Lipids in Plant Autophagy – LBM

Head: Amélie BERNARD

amelie.bernard@u-bordeaux.fr
INRAE Bordeaux-Aquitaine, Avenue Edouard Bourlaux, Villenave-d'Ornon, France
R&D team

Structure and function of bacterial nanomachines – MFP

↗ Website + Info

R&D team: Structure and function of bacterial nanomachines – MFP

Head: Rémi FRONZES

remi.fronzes@u-bordeaux.fr
Institut Européen de Chimie et Biologie, Rue Robert Escarpit, Pessac, France

Key publications in 2021

  • Mehidi, A., Kage, F., Karatas, Z., Cercy, M., Schaks, M., Polesskaya, A., Sainlos, M., Gautreau, A.M., Rossier, O., Rottner, K., and Giannone, G. (2021). Forces generated by lamellipodial actin filament elongation regulate the WAVE complex during cell migration. Nat Cell Biol 23, 1148-1162. 20211104. Nov, 10.1038/s41556-021-00786-8
  • Ito Y, Esnay N, Platre MP, Wattelet-Boyer V, Noack LC, Fougère L, Menzel W, Claverol S, Fouillen L, Moreau P, Jaillais Y, Boutté Y. Sphingolipids mediate polar sorting of PIN2 through phosphoinositide consumption at the trans-Golgi network. Nat Commun. 2021 Jul 13;12(1):4267. doi: 10.1038/s41467-021-24548-0.
  • Bessa-Neto, D., Beliu, G., Kuhlemann, A., Pecoraro, V., Doose, S., Retailleau, N., Chevrier, N., Perrais, D., Sauer, M., and Choquet, D. (2021). Bioorthogonal labeling of transmembrane proteins with non-canonical amino acids unveils masked epitopes in live neurons. Nat Commun 12, 6715. 20211118. Nov 18, 10.1038/s41467-021-27025-w
  • Rosendale, M., Flores, J., Paviolo, C., Pagano, P., Daniel, J., Ferreira, J., Verlhac, J.B., Groc, L., Cognet, L., and Blanchard-Desce, M. (2021). A Bottom-Up Approach to Red-Emitting Molecular-Based Nanoparticles with Natural Stealth Properties and their Use for Single-Particle Tracking Deep in Brain Tissue. Adv Mater 33, e2006644. 20210422. Jun, 10.1002/adma.202006644
  • de Senneville, B.D., Khoubai, F.Z., Bevilacqua, M., Labedade, A., Flosseau, K., Chardot, C., Branchereau, S., Ripoche, J., Cairo, S., Gontier, E., and Grosset, C.F. (2021). Deciphering tumour tissue organization by 3D electron microscopy and machine learning. Commun Biol 4, 1390. 20211213. Dec 13, 10.1038/s42003-021-02919-z