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IBDM – PiCsL

Type: Facility

Business services: Yes

Head title: Head

Head name: Cédric MATTHEWS & Nicolas BROUILLY

Contact: cedric.matthews@univ-amu.fr & nicolas.brouilly@univ-amu.fr

Website: https://www.ibdm.univ-amu.fr/fr/plateformes-scientifiques/

Node: Marseille

Location: IBDM (Institute of Developmental Biology of Marseilles), UMR 7288 Case 907, Avenue de Luminy, Marseille, France

Available service offers on this site

CLEM RT (Room Temperature)

With the help of the IBDM Lignt Microscopy Facility we can offer an comprehensive CLEM Pipeline from live fluorescence imaging to EM imaging (in 2D and 3D)
Electron microscopy

Dynamic imaging on multicellular systems (FRAP, FLIM)

Molecular live imaging

Dynamic imaging on multicellular systems (FRAP, FLIM)

Molecular live imaging

Laser nano dissection in tissues

Mechanobiology and optomanipulation

Lightsheet: with clarification or not

We work on mouse models (embryos at different stages, mouse organs, tumor samples) with solvent based clearing methods (iDisco modified, home made protocols depending on the samples).
3D imaging Multiscale and multimodal imaging

Nanoscopy (STED 3D, SMLM, DNA-PAINT, 3D SIM)

3D SIM on microorganisms
Super-resolution microscopy

Smart microscopy with deep learning on medium-throughput cellular imaging

Smart microscopy

Two photons: calcium and voltage imaging on explants in vivo/ vitro

With the help of the CircuitPhotonics platform we can offer several approaches to imaging living organisms, on brain slices with a TriMscope 1 (LaVision Biotec), in mouse brains with several…
Intravital microscopy

Workflow volume EM, TOMO TEM, SBF SEM

As Volume EM techniques we offer Electron Tomography and Serial Blockface Scanning Electron Microscopy. The targeting of a precise ROI can be achieved by integrating Light Microscopy or X-ray imaging…
Electron microscopy