The MAMBO team (MAthématiques pour l’iMagerie BiOlogique) is specialized in mathematics (optimization, learning, approximation, inverse problems) and in imaging (reconstruction and analysis). It has 2 main objectives: – Participate in the improvement of microscopy techniques (e.g. RIM, TIRF, SMLM, …) by refining their mathematical modeling and by building efficient reconstruction algorithms. – Participate in the analysis of the resulting images by developing (or using) tools to improve the quality of segmentation or classification in large volumes of data. In particular, it develops new artificial intelligence models to achieve its goals.