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MRIC (Microscopy Rennes Imaging Center)

Type: Facility

Business services: No

Head title: Head

Head name: Marc TRAMIER

Contact: marc.tramier@univ-rennes1.fr

Website: https://microscopie.univ-rennes.fr/mric-microscopy-rennes-imaging-center

Website Service: https://microscopie.univ-rennes.fr/mric-microscopy-rennes-imaging-center

Node: Bretagne-Loire

Location: 2 Avenue du Professeur Léon Bernard, 35000 Rennes, France

Available service offers on this site

Development of complex acquisitions (smart Microscopy)

The automation of fluorescence microscopy represents a challenge for the study of rare or transient events in biology and medicine. It relies on intelligent devices that integrate and interpret observed…
Smart microscopy

Development, observation and identification of specific markers on 3D models and tissue

support from sample preparation to image analysis - including visualisation of organoids/spheroids in 3D imaging. Pool of systems and expertise for these studies (transparization, staining, light sheets, etc.).
3D imaging

Molecular dynamics and interaction (F-techniques)

molecular diffusion by FRAP, FCS and SPT; macromolecular interactions by FRET-FLIM, fluorescence anisotropy and FCS-2colours; biochemical activities by FRET biosensors
Molecular live imaging

Multimodal correlative microscopy, including CLEM

Multimodal microscopy, by combining fluorescence, harmonic and electron microscopy signals, is therefore of real interest for taking advantage of complementary information and increasing the sensitivity of pathology detection to qualify…
Electron microscopy

RIM (Random Illumination Microscopy): In depth Super resolution with wide-field excitation

RIM, based on natural laser speckle illumination, is a method of choice for super-resolved imaging of living cells in depth. The idea is to combine optically resolved laser speckle illumination…
Super-resolution microscopy

Spatial super resolution (Airy Scan, NSIM, RIM, NSpark, STORM Abbelight)

spatial super resolution by ISM (Image Scanning Microscopy) with AiryScan and NSpark in confocal (Zeiss and Nikon); by structured illumination with NSIM and RIM (Nikon and prototype); by SMLM with…
Super-resolution microscopy

Unlabelled cellular or tissue imaging: SHG, autofluorescence (kratoscope), Raman, holotomography

Unlabelled imaging can be used to characterise histological sections by mapping them without treatment. It is also possible to complete the analysis using immunohistochemistry, multiplex immunoflorescence or histological staining technologies.…
Label-free imaging