Biology, physics, applied mathematics and complex systems modelling
IdFsud gathers an important task force in biology, physics, applied mathematics and complex systems modelling. These disciplines synergize to develop innovative methodologies and tools in microscopy imaging and image analysis for applications in developmental biology, cell biology, plant biology, physiopathology and neurosciences. IdF Sud gathers three core partners with internationally acknowledged expertise: BioEmergences (CNRS-IBiSA), Imagerie-Gif and Polytechnique LOB (Lab for optics & biosciences, CNRS – INSERM).
The imaging facilities of IdFsud are developed and coordinated by: Nadine Peyrieras (INAF, CNRS, Gif-sur-Yvette), Sandrine Lecart (I2BC, CNRS, Gif sur Yvette), Emmanuel Beaurepaire (Ecole Polytechnique, CNRS, Palaiseau).
The activity of the Ile-de-France Sud node (IdFsud) consists in developing novel optical biological imaging methods, in giving access to a broad range of imaging approaches to a large community, and in providing adequate training in light microscopy and CLEM.
Technological Innovations
- New non-linear contrast: probing lipid order with polarized THG. LOB. Phys Rev X (2013)
- Multicolor 2P Imaging of Brainbow tissue LOB/Inst Vision/ENS. Neuron (2014)
- 3D+time image analysis of the digital lineage trees with the BioEmergences workflow (Nature Comm. 2016)
Some of the Innovative systems operated
- Multicolor and polarisation multi-photon microscopy
- Horizontal 2-photon microscope
- Light-sheet microscopy
Tech transfer
- Biosensors & Applications
- Industrial partnershipp for light sheet microscopy
- 3D+time multiscale data reconstruction workflows
- Correlative microscopy






