Cutting-edges methods in image-based phenotyping and multi-scale tracking of therapeutic agents

The Bretagne-Loire Node is composed of three cellular and tissue imaging platforms: H2P2, MicroPICell and MRic-of the Bioimaging axis of GIS Biogenouest and research and development teams (belonging to IGDR, Numecan, Cesam, Inria-Rennes, LS2N, SFR F. Bonamy) that support the activities of these platforms.

Located in Nantes and Rennes, the three platforms have the IBiSA certification and their expertise in life imaging and pathological anatomy are complementary.

The mission of the node is to provide the latest technological and methodological advances in microscopy for an integrated understanding of cellular and tissue activities in particular for preclinical research.

The Bretagne-Loire Node has expertise in technology transfer and translational research and benefits from a privileged scientific environment due to its affiliation with the University Hospital Centres.

2021 in Numbers

  • 589 hosted projects
  • 19 publications
  • 12 training programs
  • 8 patents since 2011

Technological Innovations

Correlative microscopy  (Nature Methods 2017, Burel 2018 )

Multimodal Fluorescent organic nanoassemblies (Small 2018)

High-content screening Fluorescence Life Time, High content screening with large field of views

Label free multimodal imaging (Raman , Infra red, CARS, SHG)

Multiplexing staining

Tech transfer

Roboscopy (Inscoper, Photonlines)

Episcopic microscopy for 3D histology (Kaerlabs)

Most Innovative Systems Available for Booking

Light-sheet microscopy

TEM and cryo-microscopy

Raman microspectroscopy

Micropatterning

Structure illumination microscopy, STORM

Facility

H2P2 (Histo pathology High precision)

↗ Website ↗ Service + Info

Facility: H2P2 (Histo pathology High precision)

Head: Anthony SEBILLOT

H2P2@univ-rennes.fr
2 Avenue du Professeur Léon Bernard, 35000 Rennes, France

Services on this Facility

Service

Microscopy Technologies

Facility

MicroPICell (Tissue and cell imaging)

↗ Website ↗ Service + Info

Facility: MicroPICell (Tissue and cell imaging)

Head: Perrine PAUL-GUILLOTEAUX, Vincent GUEN

perrine.paul-gilloteaux@univ-nantes.fr & micropicell@univ-nantes.fr
8 Quai Moncousu, 44000 Nantes, France

Services on this Facility

Service

Image Data Handling

Service

Microscopy Technologies

Facility

MRIC (Microscopy Rennes Imaging Center)

↗ Website ↗ Service + Info

Facility: MRIC (Microscopy Rennes Imaging Center)

Head: Marc TRAMIER

marc.tramier@univ-rennes1.fr
2 Avenue du Professeur Léon Bernard, 35000 Rennes, France

Services on this Facility

Service

Microscopy Technologies

R&D team

CeDRE (Cell Division Reverse Engineering) lab – IGDR

↗ Website + Info

R&D team: CeDRE (Cell Division Reverse Engineering) lab – IGDR

Head: Jacques PECREAUX

jacques.pecreaux@univ-rennes1.fr
2 Avenue du Professeur Léon Bernard, 35000 Rennes, France
R&D team

Microscopy for cell biosensing team – IGDR

↗ Website + Info

R&D team: Microscopy for cell biosensing team – IGDR

Head: Marc TRAMIER

marc.tramier@univ-rennes1.fr
2 Avenue du Professeur Léon Bernard, 35000 Rennes, France
R&D team

Photoactive multimodal nanomaterials for bio-imaging and therapy – CEISAM

↗ Website + Info

R&D team: Photoactive multimodal nanomaterials for bio-imaging and therapy – CEISAM

Head: Eléna ISHOW

elena.ishow@univ-nantes.fr & contact_ceisam@univ-nantes.fr
2 Chemin de la Houssinière, Nantes, France
R&D team

SP@RTE team – IGDR

↗ Website + Info

R&D team: SP@RTE team – IGDR

Head: Gilles SALBERT

gilles.salbert@univ-rennes.fr
2 Avenue du Professeur Léon Bernard, Rennes, France