20th anniversary of IMAC Master’s program at University of Normandie!
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Category: Announcement
On September 6, the Cellular Imaging Master, created in 2004 by Delphine Burel and Ludovic Galas at the University of Rouen Normandie, celebrated its 20th anniversary in partnership with the IBiSA PRIMACEN imaging facility.
Over 50 alumni attended the event, along with the Master’s coordinators and several teaching staff members. The day began with a review of the program’s 20 years and a presentation on international collaborations with the Universities of Turku and Abo Academy in Finland, followed by a vote for the new Master’s logo!
In the afternoon, participants enjoyed fun activities such as karting, bowling, and karaoke at Espace Loisirs Rouen, fostering a convivial atmosphere among students and teachers. Everyone agreed to meet again in five years for future celebrations.
This successful anniversary was made possible thanks to the efforts of the M2 IMAC 2024 class and the support of their sponsors!
Find out more about the IMAC Master’s program here.
France-BioImaging recently participated in two major events dedicated to innovation and industrial collaboration: RDV Carnot and the Cosmetic 360 trade show. These gatherings highlighted the many applications of microscopy in addressing the specific needs of various industries, from pharmaceutical research to the cosmetics sector.
RDV Carnot: opportunities for applied innovation
For France-BioImaging, this event offers a unique opportunity to connect with companies from various sectors (pharmaceutical, food, textile) with advanced imaging needs.
Through direct exchanges, France-BioImaging members were able to better understand industry expectations in sample characterization and analysis, from immunology to textile fiber studies.
This event thus allows France-BioImaging to showcase its advanced microscopy technologies to companies seeking high-potential solutions for applied research.
Cosmetic 360: cosmetic innovation through the lens of microscopy
The Cosmetic 360 trade show is a key event for the cosmetics industry, bringing together companies from across the value chain: large groups, SMEs, start-ups, raw material suppliers, laboratories, and more.
In this sector, microscopy plays a vital role in analyzing natural ingredients, assessing cosmetic product efficacy, and ensuring formulation quality.
Beyond its scientific value, microscopy provides a marketing advantage with the high-quality images it produces, enabling brands to communicate transparently and attractively about product efficacy.
These two events underscored the strategic role of microscopy in addressing the challenges of innovation across various industries. Whether for applied research needs or marketing value, France-BioImaging continues to develop and provide cutting-edge technologies to support companies in their R&D projects.
As the infrastructure evolves, the ongoing identification of industrial needs and emerging sectors will enhance the impact of France-BioImaging’s imaging technologies, fostering collaborations that align with the goals of diverse industries. If you have already identified some needs and potential collaborations, please contact us.
Global BioImaging organizes annual international workshops calledExchange of Experience (EoE), which represent key moments for the international imaging community to come together and discuss common goals, trends and challenges in running open access imaging facilities across the globe.
This year’s host has been our Japanese colleagues from ABis (Advanced Bioimaging Support). We took the opportunity to take part in their annual meeting, one day ahead of the GBI EoE. The program highlighted groundbreaking research, including studies on genome structure in single human cells (Jan Elleberg) and new methods for analyzing multi-cellular dynamics (Tomomi Nemoto). Other high-interest topics included big data acquisition (Hideharu Mikami), expansion microscopy (Xiaoyu Shi) and cognitive biases in neuroimaging (Makiko Yamada).
This 9th edition brought together the global imaging community in Okazaki to discuss shared goals, trends and challenges in managing open-access imaging facilities worldwide. The focus of this edition, “Image Data Horizons – Global Strategies for Accessible Knowledge”, encouraged a rich exchange on practical approaches to data sharing, management, and accessibility.
France-BioImaging’s Data mission co-officer, Perrine Paul-Gilloteaux, presented the FBI.Data project, showcasing France-BioImaging’s leadership data management – recognized as a model approach within the international community.
We also attended the first FoundingGIDE meeting, where we delved more deeply into the steps that image data scientists, supported by funders, decision-makers, and corporate partners, can take to advance towards a Global Image Data Ecosystem (GIDE).
As always, it was a pleasure to meet all the colleagues from the international bioimaging community!
As the 2024 edition of the France-BioImaging Image Contest is still running, we wanted to highlight our previous winners and their projects. Here is a quick throwback to our 2023 winners.
Before getting to the heart of the matter, we want to remind you that you still have time (before November 8th) to submit your best images and try to win your registration fees for one 2025 microscopy-related event! Please make sure you upload your images on the following link:
Last year, we enjoyed the winning images submitted for their artistic take and their quality. Thanks to Laurent LE, Gonzalo QUIROGA-ARTIGAS and Hugues LELOUARD for their beautiful images!
1st Place: Laurent LE, Lévêque-Fort Team, Institut des Sciences Moléculaires d’Orsay
“In the blink of an eye”
COS7 fixed cell. Alpha-tubulin labeled with DNA-PAINT and imaged with Atto 647N. Axial information is obtained by virtual-SAF measurement known as DONALD.
SMLM Fluorescence Microscopy with DNA-PAINT with DONALD detection
Laurent LE is a Post-Doc researcher in the Sandrine Lévêque-Fort Team at Institut des Sciences Moléculaires d’Orsay. His goal is to develop new techniques for time-resolved microscopy and single molecule localization microscopy. During his PhD he especially learned toperform 3D SMLM with SAF light measurement named DONALD. This technique enables to have an isotropic three-dimensional localization precision of 20 nm within an axial range of around 150 nm above the coverslip.
During one of his trainings on the DONALD setup, he acquired this image with a nice round shape that looks like an eye. This image represents the alpha-tubulin of a fixed COS7 cell, labelled with DNA-PAINT and imaged with Atto 647N. The axial information is obtained by DONALD.
Thanks to the France-Bioimaging Image Contest, Laurent participated to the international conference FOM (Focus On Microscopy) in Genoa (Italy). This event is the most important one for his research community.
2nd Place: Gonzalo QUIROGA-ARTIGAS, Team Contrôle cytoplasmique de la stabilité du génome, Centre de recherche en Biologie Cellulaire de Montpellier
“Tardigrade embryos protected by mother’s molt”
Tardigrades commonly align the time of molting with egg laying. In this image we observe a tardigrade molt covering three developing embryos (DNA in white). The microscopy technology applied was confocal microscopy, and the research aimed to investigate the synchronization of embryo development in tardigrades.
Confocal microscopy
Gonzalo QUIROGA-ARTIGAS is a Post-Doc scientist in the Team “Cytoplasmic Control of Genome Instability” of the Centre de Recherche en Biologie cellulaire de Montpellier (CRBM-UMR5237). His research background is centered on Evolution and Developmental Biology (EvoDevo), a broad field that integrates knowledge from phylogenetics, cell and molecular biology, genetics and genetic engineering, as well as developmental biology and evolution. He is currently undertaking his second postdoctoral position, focusing on the study of the tardigrade Hypsibius exemplaris. Tardigrades are microscopic animals known for their extreme resistance to various stressors, and his research aims to uncover the mechanisms that enable them to endure such conditions. He is conducting this research in Dr. María Moriel-Carretero’s lab at the CRBM in Montpellier. His goal is to become a CNRS researcher in the years to come.
His image depicts the cuticle (or exoskeleton) of a tardigrade protecting three developing embryos. Tardigrades typically couple the moment of cuticle shedding with that of egg laying, a strategy designed to provide an extra layer of protection, ensuring the eggs survive and successfully develop into the next generation. The study aimed to assess the synchrony of embryonic development in eggs laid by the same mother within the same cuticle. This image was captured after staining the animal with a live dye (MemBrite Cell Surface Staining Kit), which highlights the cuticular structures, and a DNA stain (DAPI). A confocal Z-stack of each channel was processed using different depth LUTs in ImageJ, then merged to create the final image.
France-Bioimaging sponsored his participation to the Euro Evo Devo congress (EED) in Helsinki, Finland, in June 2024. This event brought together nearly 700 researchers from around the world, all sharing a passion for this research focus, to gather here for several days and share their ongoing projects. He attended the Arthropod satellite meeting, where he presented a current project using tardigrades as experimental models and received plenty of feedback. He also presented a poster at the main meeting and unlocked numerous potential collaborations, as many researchers showed interest in this animal model.
“Altogether, this meeting has been a fantastic opportunity for me. I was able to share my ongoing projects with the EvoDevo community, which has greatly stimulated my research progress. Additionally, the excellent atmosphere throughout the congress, the impeccable organization, and the collaborations I unlocked have made this experience wonderful both personally and professionally, opening new networking possibilities for my present and future endeavors” says Gustavo Quiroga-Artiguas.
3rd Place: Hugues LELOUARD, Gorvel team, Centre d’Immunologie de Marseille Luminy
“Intestinal octopus“
Small intestine section from a LyzM-eGFP mouse containing one Peyer’s patch and stained for proliferative cells (Ki-67, yellow), Paneth cells (UEA-I, blue), epithelial cells (EpCAM, magenta), naive B cells (IgD, red), T cells (CD3, orange), helper T cells/macrophages (CD4, cyan), phagocytes (CD11c, turquoise), monocyte-derived phagocytes (GFP, green).
10-color spectral confocal microscopy
Confocal microscopy
Hugues LELOUARD is a CNRS research director working in the field of mucosal immunology at the Centre d’Immunologie de Marseille Luminy (CIML). His research focuses on understanding the role of Peyer’s patch phagocytes in initiating the intestinal immune response.
His image depicts a section of the small intestine from a LyzM-eGFP mouse, featuring a Peyer’s patch, captured using a Zeiss LSM 980 spectral confocal microscope with a mosaic setting of 20 tiles. Spectral confocal microscopy enables the simultaneous imaging of multiple parameters without requiring iterative acquisition steps. Here, staining highlights proliferative cells (Ki-67, yellow), Paneth cells/goblet cells/mucus (UEA-I, blue), epithelial cells (EpCAM, magenta), naïve B cells (IgD, red), T cells (CD3, orange), helper T cells/macrophages (CD4, cyan), phagocytes (CD11c, turquoise) and monocyte-derived phagocytes (GFP, green). This image illustrates the spatial distribution of phagocytes (green and turquoise) within the complex microenvironment of Peyer’s patches. Understanding their role in pathogen uptake, degradation and antigen presentation to effector immune cells is crucial for unravelling the mechanisms that initiate the intestinal adaptive immune response.
In a highly competitive call part of the National France 2030 Plan, France-BioImaging was selected to receive special funding to upgrade its technology offer and implement tomorrow’s imaging technological and methodological developments.
Securing Next-Generation Instruments for Biological Imaging
In recent decades, innovations in microscopy have led to technological revolutions that had strong impacts in important societal fields such as agronomy, marine biology and human health. Life scientists need to have easy access to these technologies and France-BioImaging, with 30 top-notched facilities and thousands of users, is best placed to develop, implement and give access to the latest imaging technologies to the national and international community.
In 2024, the French Ministry of Higher Education and Research allocated 80 M€ for a call dedicated to the National Research Infrastructures in Biology and Health (Programme Investissement d’Avenir) to keep their research and technologies at the highest level of excellence.
France BioImaging was a laureate of the call with its project Biological Imaging Next-Generation Instruments (BIOGENI).
In this project, 1.9 M€ will be invested to rejuvenate and upgrade existing technologies and 7.3 M€ will serve to implement new technologies, paving the way for the use of next-generation imaging methods by our users.
The BIOGENI project will both strengthen the visibility and attractivity of France-BioImaging, and provide our researchers access to the most powerful and needed imaging technologies. This includes new technologies in super-resolution and single molecule tracking, multiscale correlative microscopy, light sheet microscopies, high-content and multiplexed imaging, new contrasts and preclinical microscopy. The equipment purchased thanks to BIOGENI will be complemented by new human resources dedicated to data management and image analysis, provided by the Partner Institutions of the infrastructure. This will enable proper data management and analysis, as many of the new technologies deliver very large datasets requiring dedicated tools.
2023 and 2024 were busy years for France-BioImaging. The infrastructure not only made a winning grant proposal to ensure the upgrade of existing technologies and the implementation of new ones, but successfully passed the evaluation of the 2020-2024 period, ensuring allocation of its running budget for the next few years.
IBISA / INBS Interdisciplinary Day : A feedback on the access call to Structural biology, Biological imaging and Proteomics facilities. November 19th 2024 – IGBMC, Ilkirch
The three national infrastructures ProFi, France-BioImaging and FRISBI along with the GIS IBiSA are pleased to welcome you to Strasbourg for the 1st edition of a feedback meeting in relation to a funded access call to IBiSA-labelled facilities. This meeting is a satellite meeting of the 8th France-BioImaging Annual Meeting (November20th et 21th) and the 8th FRISBI annual users meeting (November 18th)
Meeting registration: Registration is free of charge but you must be registered to attend the meeting. Please kindly fill the form: https://forms.gle/EY4XSwZNWaJSUmsh6
The RIC (Réseau d’Imagerie Cellulaire Paris-Saclay) is pleased to invite you to a conference on Super-Resolution Microcopy on October 3rd. The aim is to raise awareness of super-resolution microscopies and their practical applications in the study of fundamental biological mechanisms.
Going to Rendez-Vous Carnot 2024? Drop by our booth !
On October 16th, we will at the Palais des Congrès de Massy for the Rendez-Vous Carnot 2024! This is the sixth time that we will attend the forum as an exhibitor, in the Research Infrastructures Village. We are going to present France-BioImaging R&D ecosystem and the multiple advanced biological microscopy technology developments taking place on FBI imaging platforms and R&D teams. With 109 laboratories and 70 technologies, we offer services, training and research collaborations for the private sector. From healthcare and cosmetics to food-processing and environment, microscopy can answer the needs of a wide range of markets and sample types.
If you are attending the Rendez-Vous Carnot as well, be sure to drop by our booth (at the Research Infrastructure Village) and meet some of our colleagues at the venue:
La valorisation de l’activité de recherche implique de nombreuses modalités. Parmi elles, la diffusion des résultats au-delà du cercle communautaire académique peut prendre la forme de la protection intellectuelle et de la commercialisation, ouvrant ainsi la perspective de rendre accessible une technologie au plus grand nombre et d’en assurer une valorisation monétaire. Cette étape demeure cependant pratiquée par un nombre limité de chercheurs, entre autres par méconnaissance de l’aventure du transfert.
L’objectif de cette journée est précisément de pallier ce manque au travers de témoignages variés de chercheurs, de directeurs de startups, de responsables d’entreprises, et d’acteurs des services de valorisation qui ont converti un résultat scientifique dans le domaine de l’imagerie biologique en un produit ou un service commercialisé. Ils décriront leur motivation et leur parcours avec ses difficultés et ses satisfactions. La journée prévoit aussi un temps de rencontre et une table ronde finale destinée à partager d’autres témoignages et à répondre aux interrogations.
We are delighted to announce that the GDR Imabio, in partnership with France-Bioimaging, is organizing the next “High Resolution 3D Microscopy in Biology: Developments & Applications”, which will cover a wide range of topics, from new instrumental approaches to biological applications, particularly for imaging in depth and/or in complex environments (Super-resolution – Expansion microscopy – STORM in depth – in vivo STED – in vivo 2 photon microscopy – Phase and Label free imaging – Structured Illumination Microscopy – Light sheet microscopy – Adaptive optics – Tissue imaging – Organoids… ).
The event will be held on the campus of the Université Paris Saclay, at the ISMO, from Monday afternoon, October 7, starting at 2pm, to Tuesday, October 8, around 4pm (several TGV trains arrive at Massy Palaiseau, 15 minutes from the campus). We have already confirmed the participation of various speakers (Ralf Jungmann, Erdinc Sezgin, Sophie Brasselet, Gaëlle Recher, Virgile Viasnoff), and the call for oral and poster contributions is now open. Submit your abstract before September 25th through the registration form below.
The days will be free of charge, but registration is compulsory, as the size of the amphitheatre will limit participation to 80 registered participants.
This workshop will take place at the Institut Fresnel (FBI Marseille node) from November 12th to 14th , 2024.
Fluorescence polarization microscopy allows measurements of the orientation of molecules probed by various techniques. Through hands-on experiments, we will demonstrate their suitability for biological applications on a range of sample types, including cells and organisms. The Institut Fresnel is a pioneer in this field, developing unique microscopes to probe molecular orientation – an intrinsic property of molecules that is measurable with all types of microscopes but often remains inaccessible.
The workshop aims to offer (1) a theoretical basis for understanding how one can probe molecular orientation, (2) ample time for practical experiments, and (3) opportunities for formal and informal discussions on technical details and biological applications.
Free registration includes accommodation, transport, and meals (except for the evening of November 13th).
Candidates whose research projects align best with the workshop’s focus will be selected, with preference given to members of the France-BioImaging (FBI) infrastructure.
Following the successful COMULIS conferences in Austria, Sweden and Cyprus, the next COMULIS conference will expand beyond European borders.
The upcoming COMULISglobe Conference will take place at Stellenbosch University (https://www.sun.ac.za), South Africa from January 20th-21st, 2025.
This conference is designed to bring global experts, researchers, facility staff and exhibitors together from different imaging modalities to stimulate knowledge exchange and the formation of new collaborations. The conference program offers an attractive combination of oral presentations and posters regarding CLEM techniques from sample preparation to image analysis.
For attendees from low or middle-income* countries, the conference registration fee is USD 50 for students and USD 100 for non-students. Participants from high-income countries are required to pay a fee of USD 250. This fee includes meals and refreshments for the duration of the conference.
This exciting scientific meeting will take place as an in-person event.
January 22nd – 24th a Correlated Multimodal Imaging workshop will be held at Stellenbosch University as well as Tygerberg Campus. The workshop is free if charge, but a selection process will be followed.
Only participants of the conference are eligible for the workshop.
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