The 7th edition of OPTOGEN will bring developers and end-users in the field of Optogenetics and Neurophotonics together. It will be a great occasion to meet in person for stimulating discussions and to reignite collaborations.
Registration and abstract submission are open.
Early registration will close on April 15th.
Thanks to the support of the IHU Foresight and of the sponsors, inscription is free for students registered before April 15th and some travel grants will be available.
Euro-BioImaging is organizing a third online User Forum on Tuesday, April 5, 2022 from 14:00-17:00 CEST. The topic is “At the Forefront of Neuroscience.”
This event will highlight the importance of cutting-edge imaging technologies in support of brain research and showcase the specific expertise available at our Nodes across Europe through case studies presented in tandem with the research community.
In addition, keynote presentations from Hervé Boutin, University of Manchester, and Selma Ding, Max Planck Institute for Animal Behavior, will further reveal the potential of biological and biomedical imaging technologies to boost brain research.
The deadline for this inter-infrastructure access call is 15 April 2022.
All submitted proposals will be peer-reviewed by independent experts and the final funding will be approved by a committee comprising 2 representatives from each infrastructure as well as representatives from GIS IBISA. We advise the project PI to contact the chosen facilities in order to set-up the optimal experimental design.
Understanding how development is coordinated in multiple tissues and gives rise to fully functional organs or whole organisms necessitates microscopy tools. Over the last decade numerous advances have been made in live-imaging, enabling high resolution imaging of whole organisms at cellular resolution. Yet, these advances mainly rely on mounting the specimen in agarose or aqueous solutions, precluding imaging of organisms whose oxygen uptake depends on ventilation.
Engineers from the Institut Curie and Institut Jacques Monod implemented a multi-view multi-scale microscopy strategy based on confocal spinning disk microscopy, called Multi-View confocal microScopy (MuViScopy).
MuViScopy enables live-imaging of multiple organs with cellular resolution using sample rotation and confocal imaging without the need of sample embedding. They illustrated the capacity of MuViScopy by live-imaging Drosophila melanogaster pupal development throughout metamorphosis, highlighting how internal organs are formed and multiple organ development is coordinated. They foresee that MuViScopy will open the path to better understand developmental processes at the whole organism scale in living systems that require gas exchange by ventilation.
Olivier Leroy, Eric van Leen, Philippe Girard, Aurélien Villedieu, Christian Hubert, Floris Bosveld, Yohanns Bellaïche, Olivier Renaud; Multi-view confocal microscopy enables multiple organ and whole organism live-imaging. Development 15 February 2022; 149 (4): dev199760. doi: https://doi-org.insb.bib.cnrs.fr/10.1242/dev.199760
The MuViScope was co-funded by France-BioImaging.
The IGDR (Institut de Génétique et de Développement de Rennes) and MRic facilities in Rennes organize an EMBO practical course “Sensing biophysical properties in living samples using light microscopy” from July 4th to July 9th 2022.
Le Réseau d’Imagerie Cellulaire Paris-Saclay organise en avril prochain une visioconférence de 2 heures portant sur le thème de l’imagerie des organoïdes.
Titre : Pipeline Organoïdes de A à Z : Fabrication, Transparisation, Acquisition et Analyse d’images.
Thématique : Le RIC Paris-Saclay vous propose une sorte de pipeline sur l’imagerie des modèles organoïdes qui vous permettra de mieux appréhender l’ensemble du processus de leurs fabrications, leurs modes de transparisation, l’analyse des images 3D associées à ce type d’échantillon épais, et pour finir, l’importance de l’étude de ces modèles chez l’homme pour développer de nouveaux outils thérapeutiques.
Date : 14 avril 2022 Horaire : 14h à 16h
Programme : Auto-organisation cellulaire en systèmes 3D par imageries optiques — Tissue clearing : Adapted protocols for small samples — Analyses d’images et reconstruction 3D — Applications en Recherche translationnelle (Organoïdes hépatiques humains).
The thematic institute of molecular and structural basis of life sciences of the French National Alliance for Life Sciences and Health (Aviesan) has identified cellular (cryo) electron microscopy as a priority area to be developed in the future. To better understand the functional behaviour of living organism, it becomes increasingly important to describe its structural organization from atomic scales to integrated, multi-component biological systems. Recent developments in imaging have drastically transformed our perception of the molecular organization and of the dynamic interactions of molecules in cellular systems.
That is why, they are organizing a 2-days meeting entitled “Symposium on recent developments in cellular electron microscopy”, and dedicated to the latest progresses in the field of cellular electron microscopy at the interface with fluorescent microscopy and structural biology. The meeting is built around 4 scientific sessions, namely volumetric imaging, cryo-electron tomography, correlative light and electron microscopy, and new technological developments. The meeting is for molecular and cellular biologists to have an overview of the latest results and concepts that develop at this interface.
Due to the sanitary situation, vaccination pass and face masks are mandatory to attend the meeting.
For users from a unit attached to the INSB who do not usually use Research Infrastructures’ services for their projects
For access to technologies and related expertise
For access to expertise in data analysis
The scientific project must be a project in the process of being finalized
The field of Life Sciences has undergone major developments over the past two decades. The change of scales, both in spatial and temporal resolution, and the integration of data from a wide variety of sources, as induced by the development of technologies, have revolutionized the exploration of life. These technologies call for expensive investments and specific know-how, carried out by highly qualified personnel, having led to the creation of common infrastructures such as research infrastructures (RIs) open to the entire scientific community. The Institut des Sciences Biologiques (INSB) from Centre National de la Recherche Scientifique (CNRS) is launching a call for projects to fund full access to the national infrastructures in health and biology “INBS Access to national research infrastructures”. This call aims to encourage new teams to use the services offered by Research Infrastructures like France-BioImaging to help their research project. The objective is to demonstrate the significant impact of these services to improve the quality of their results (resolution, reproducibility, change of scale, etc.) or to help remove technological barriers.
Access to Research Infrastructures is open to the entire French and international scientific community, with costs covered by facility fee billing. The purpose of this program is to facilitate and finance access to these infrastructures in order to encourage teams who do not usually use the research infrastructures’ services to become RIs users, to validate the contribution that the infrastructures could make to their research topic, to remove barriers that impair the completion or finalization of an ongoing project. As National Research Infrastructure, France-BioImaging is eligible and can host the applicant’s project on one of its facilities. Several types of access can be supported by this call for projects:
Access to technologies and related expertise
Access to expertise in data analysis
In addition to the costs of access to infrastructure, travel/mission costs, as well as consumables that are not covered by the costs of access to infrastructure, may be covered. The funding for each project will be in the range of 10 to 30 K€.
Instructions for submission
This is two-stage submission. The first stage consists of a letter of intent, prepared by the scientific leader of the project, outlining the project in which the application fits and highlighting the barriers that could be removed by access to IRs. This letter of intent must also be signed by the director of the applicant’s unit. The identification of the infrastructures to access is possible at this stage but not mandatory. The deadline for submission of this letter is Friday 4th March 2022.
The second phase consists of a consultation between the INSB and the national Research Infrastructures. This will lead to putting the applicant in contact with the infrastructures that are able to meet the expressed needs, in order to evaluate the feasibility and to establish the budget of the final proposal. This stage will lead to the final submission of the project, signed by the heads of the involved IR(s), no later than Friday 8th April 2022.
Project eligibility and selection criteria
The scientific leader of the project should be in a unit attached to the INSB.
Access to the infrastructure must be fully implemented before 31/12/2022 (deadline for the use of funds)
The scientific project must be a project in the process of being finalized.
Access to infrastructure must unlock or accelerate the project. The start of a scientific project is not eligible for this call.
The letter of intent (maximum of three pages including figures) accompanied by a CV of the project leader (maximum of two pages) must be sent before Friday 4th March 2022 to the following address: email@example.com.
France-BioImaging is launching a call to have up to two new Nodes joining the infrastructure.
In 2022, France-BioImaging gathers 21 biological imaging facilities and 54 R&D teams specialized in biological imaging (see https://france-bioimaging.org/). It is structured in 6 local Nodes (Bordeaux, Bretagne-Loire, Ile-de-France-Sud, Marseille, Montpellier, Paris) and one transversal Node dedicated to bioimage informatics (IPDM). France-BioImaging is also the French node of Euro-BioImaging ERIC (see https://www.eurobioimaging.eu/).
The objectives of France-BioImaging are to promote the dissemination of the latest advances in all technologies and methods related to biological imaging, and their adoption by the users of the facilities that constitute the infrastructure.
In order to expand its technology and expertise portfolio and to provide the best possible geographical coverage to life scientists across France, France-BioImaging invites node candidates to submit their letter of intent here before May 31st, 2022.
Node candidates should:
Be made up of imaging facilities and R&D teams specialized in biological imaging, not necessarily grouped on the same campus but with a territorial logic.
Demonstrate readiness to provide open user access. The facilities must be open to the outside world beyond the regional level, i.e. to the national and international levels. Each Facility must have a valid IBiSA label, or must be in the process to have their integration in an already existing IBiSA facility validated in 2023, or must obtain this label in 2023. Each facility should have a structured organization and cost accounting. The facilities must have a reservation website for access to the equipment and a user training program. The facilities will be required to have or commit to a data management plan.
Gather R&D teams with a high degree of innovation and demonstrate a willingness to collaborate with the facilities. They must explain and demonstrate their technology and/or know-how transfer methods, particularly towards the local platforms, but not exclusively.
Bring real added value in relation to the current status of France-BioImaging, whether in terms of technologies, methodologies, scientific themes, novel user communities,… (for more information, visit the FBI website and consult the service offer). This is a key criteria.
Have an integrated and effective governance model.
More information on the selection criteria, expected commitments and documentation that needs to be provided can be found here.
Node selection will be done via a two-step process:
a letter of intent (deadline May 31st, 2022): the form to be completed is available here
a full application (deadline September 30th, 2022).
Applications will be reviewed at both steps by an International Board and decisions will be communicated at the end of 2022.